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Yvonne Maldonado

Academic Appointments

Key Documents

Contact Information

  • Clinical Offices
    Pediatric Infectious Disease 730 Welch Rd 2nd Floor MC 5884 Palo Alto, CA 94304
    Tel Work (650) 721-5805 Fax (650) 725-8040
  • Academic Offices
    Personal Information
    Email Tel (650) 723-5682
    Alternate Contact
    Nancy Wilkening Administrative Assistant Tel Work 650-498-6277
    Not for medical emergencies or patient use

Professional Overview

Clinical Focus

  • Infectious Diseases, Pediatric
  • Pediatric Infectious Disease

Administrative Appointments

  • Medical Director, Infection Control, LPCH (2006 - present)

Professional Education

Residency: John Hopkins Hospital MD (1984)
Internship: Stanford University School of Medicine CA (1982)
Fellowship: Centers for Disease Control and Prevention GA (1988)
Board Certification: General Pediatrics, American Board of Pediatrics (1986)

Postdoctoral Advisees

Marisa Holubar

Graduate & Fellowship Program Affiliations

Scientific Focus

Current Research Interests

The research I have conducted has been focused on epidemiologic aspects of viral vaccine development and prevention of perinatal HIV transmission. A major project has been to identify the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) among children living in developing areas of the world, where OPV immunogenicity is poor. We have identified several factors which affect the poor immunogenicity of OPV and will conduct clinical studies to attempt to improve immunogenicity. We are now working on ways to understand the transmission and circulation of polio vaccine derived viruses, which may cause polio, and how to use this information in global eradication of polio. I also work on perinatal HIV infection, including strategies to prevent breastfeeding transmission in developing settings as well as understanding how to maximize prevention strategies among pregnant women in developed countries.

A second recent project has been to define the ontogeny of the immune response to measles vaccine among young infants. The purpose is to identify specific humoral and cell-mediated immune responses to measles vaccine which affect vaccine immunogenicity and induce the immunosuppressive effects associated with measles vaccination.

A final project I have conducted since 1989 involves a long term natural history study of infants with perinatal HIV exposure and infection. This computer-based study involves following all HIV-exposed and infected infants living in the Northern California and defining factors associated with progression of HIV-related disease.

Publications

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