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David K. Stevenson, M.D.
Academic Appointments
- Professor, Pediatrics - Neonatal and Developmental Medicine
- Member, Bio-X
- Member, Child Health Research Institute
- Professor (By courtesy), Obstetrics & Gynecology
Key Documents
Contact Information
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Clinical Offices
Neonatal Intensive Care Unit 725 Welch Rd 2 West Palo Alto, CA 94304 Tel Work (650) 497-8800 Fax (650) 725-8351Practices at Lucile Packard Children's Hospital
- Academic Offices
Personal Information Email Tel (650) 723-5711 Tel (650) 724-6966
Professional Overview
Clinical Focus
- Neonatal-Perinatal Medicine
- Neonatology
Administrative Appointments
- Co-Director, Stanford Center for Clinical and Translational Education and Research (SCCTER) (2008 - present)
- Vice Dean, Stanford University School of Medicine (2006 - present)
- Senior Associate Dean for Academic Affairs, Stanford University School of Medicine (2001 - present)
- Director, Charles B. and Ann L. Johnson Center for Pregnancy and Newborn Services, Lucile Packard Children's Hospital at Stanford (1997 - present)
- Harold K. Faber Professor of Pediatrics, Stanford University School of Medicine (1992 - present)
- Chief, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine (1989 - 2007)
Honors and Awards
- Member, Institute of Medicine of the National Academies, National Academy of Sciences (2012)
- Jonas Salk Award for Leadership in Prematurity Prevention, March of Dimes Foundation (2011)
- Maureen Andrew Mentor Award, Society for Pediatric Research (2011)
- Albion Walter Hewlett Award, Stanford University School of Medicine (2009)
- Alwin C. Rambar-James B.D. Mark Award for Excellence in Patient Care, Stanford University School of Medicine (2009)
- Joseph W. St. Geme, Jr. Education Award, Western Society for Pediatric Research (2009)
Professional Education
| Residency: | University of Washington School of Medicine WA (1977) |
| Internship: | University of Washington School of Medicine WA (1976) |
| Medical Education: | University of Washington School of Medicine WA (1975) |
| Board Certification: | Neonatal-Perinatal Medicine, American Board of Pediatrics (1979) |
| Board Certification: | General Pediatrics, American Board of Pediatrics (1979) |
| Fellowship: | Stanford University Medical Center CA (1979) |
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
Our research is focused on the study of the ontogeny and control of heme catabolism and bilirubin production in the developing neonate. A better understanding of the role of increased bilirubin production in neonatal jaundice and the prevention of hemolytic jaundice has remained an overall objective of our program. To this end, we are actively investigating a more targeted, preventive approach to the diagnosis and treatment of newborns, who are high producers of the pigment and/or unable to efficiently eliminate bilirubin, thus leading to an accumulation of the pigment in circulation and tissues, which may lead to irreversible neurologic injury. Control of bilirubin production is a logical strategy, but has unexplored consequences for the immature mammal. Thus, we are studying the pivotal role of heme oxygenase (HO), the rate-limiting enzyme in the production of bilirubin, under a variety of commonly encountered pathological conditions, such as infection and hypoxia-ischemia, as well as in anti-oxidant defense, immune response and the regulation of hematopoiesis. In support of the above interests, studies are in progress, which are designed to screen a variety of metalloporphyrins and other compounds for maximum in vitro and in vivo efficacy with minimal side effects; to determine the ontogeny of the HO enzyme system in various murine tissues, focusing on perturbations resulting from treatment with HO inhibitors; and further to develop and test new technologies for noninvasive or minimally-invasive measurements of in vivo metabolism that could be used for diagnostic and monitoring purposes.
Clinical Trials
- Not Recruiting Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure
- Not Recruiting Early Blood Pressure Management in Extremely Premature Infants
- Recruiting Vitamin E for Extremely Preterm Infants
- Recruiting Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis
- Recruiting Late Hypothermia for Hypoxic-Ischemic Encephalopathy
Publications
- Transdisciplinary translational science and the case of preterm birth. J Perinatol. 2013; (4): 251-8
- A deficiency in haem oxygenase-1 induces foetal growth restriction by placental vasculature defects. Acta Paediatr. 2012; (8): 827-34
- Effect of light exposure on metalloporphyrin-treated newborn mice. Pediatr Res. 2012; (2): 161-8
- Metalloporphyrins - an update. Front Pharmacol. 2012: 68
- Bilirubin production and the risk of bilirubin neurotoxicity. Semin Perinatol. 2011; (3): 121-6
- Effects of zinc deuteroporphyrin bis glycol on newborn mice after heme loading. Pediatr Res. 2011; (5): 467-72
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