Publications
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Caulobacter chromosome in vivo configuration matches model predictions for a supercoiled polymer in a cell-like confinement.
Hong SH,
Toro E, Mortensen KI, de la Rosa MA, Doniach S, Shapiro L, Spakowitz AJ, McAdams HH.
Proc Natl Acad Sci U S A.
2013;
110
(5):
1674-9
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Compaction and transport properties of newly replicated Caulobacter crescentus DNA.
Hong SH,
McAdams HH.
Mol Microbiol.
2011;
82
(6):
1349-58
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Direct inference of protein-DNA interactions using compressed sensing methods.
AlQuraishi M,
McAdams HH.
Proc Natl Acad Sci U S A.
2011;
108
(36):
14819-24
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The architecture and conservation pattern of whole-cell control circuitry.
McAdams HH,
Shapiro L.
J Mol Biol.
2011;
409
(1):
28-35
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The essential genome of a bacterium.
Christen B,
Abeliuk E, Collier JM, Kalogeraki VS, Passarelli B, Coller JA, Fero MJ, McAdams HH, Shapiro L.
Mol Syst Biol.
2011:
7
528
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An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation.
Tan MH,
Kozdon JB, Shen X, Shapiro L, McAdams HH.
Proc Natl Acad Sci U S A.
2010;
107
(44):
18985-90
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System-level design of bacterial cell cycle control.
McAdams HH,
Shapiro L.
FEBS Lett.
2009;
583
(24):
3984-91
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Three enhancements to the inference of statistical protein-DNA potentials.
AlQuraishi M,
McAdams HH.
Proteins.
2013;
81
(3):
426-42
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Assembly of the Caulobacter cell division machine.
Goley ED,
Yeh YC, Hong SH, Fero MJ, Abeliuk E, McAdams HH, Shapiro L.
Mol Microbiol.
2011;
80
(6):
1680-98
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The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.
Umbarger MA,
Toro E, Wright MA, Porreca GJ, Baù D, Hong SH, Fero MJ, Zhu LJ, Marti-Renom MA, McAdams HH, Shapiro L, Dekker J, Church GM.
Mol Cell.
2011;
44
(2):
252-64
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Caulobacter PopZ forms a polar subdomain dictating sequential changes in pole composition and function.
Bowman GR,
Comolli LR, Gaietta GM, Fero M, Hong SH, Jones Y, Lee JH, Downing KH, Ellisman MH, McAdams HH, Shapiro L.
Mol Microbiol.
2010;
76
(1):
173-89
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High-throughput identification of protein localization dependency networks.
Christen B,
Fero MJ, Hillson NJ, Bowman G, Hong SH, Shapiro L, McAdams HH.
Proc Natl Acad Sci U S A.
2010;
107
(10):
4681-6
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The caulobacter Tol-Pal complex is essential for outer membrane integrity and the positioning of a polar localization factor.
Yeh YC,
Comolli LR, Downing KH, Shapiro L, McAdams HH.
J Bacteriol.
2010;
192
(19):
4847-58
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Dynamic chromosome organization and protein localization coordinate the regulatory circuitry that drives the bacterial cell cycle.
Goley ED,
Toro E, McAdams HH, Shapiro L.
Cold Spring Harb Symp Quant Biol.
2009:
74
55-64
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Why and how bacteria localize proteins.
Shapiro L,
McAdams HH, Losick R.
Science.
2009;
326
(5957):
1225-8
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Architecture and inherent robustness of a bacterial cell-cycle control system.
Shen X,
Collier J, Dill D, Shapiro L, Horowitz M, McAdams HH.
Proc Natl Acad Sci U S A.
2008;
105
(32):
11340-5
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Caulobacter requires a dedicated mechanism to initiate chromosome segregation.
Toro E,
Hong SH, McAdams HH, Shapiro L.
Proc Natl Acad Sci U S A.
2008;
105
(40):
15435-40
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Small non-coding RNAs in Caulobacter crescentus.
Landt SG,
Abeliuk E, McGrath PT, Lesley JA, McAdams HH, Shapiro L.
Mol Microbiol.
2008;
68
(3):
600-14
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A DNA methylation ratchet governs progression through a bacterial cell cycle.
Collier J,
McAdams HH, Shapiro L.
Proc Natl Acad Sci U S A.
2007;
104
(43):
17111-6
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High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons.
McGrath PT,
Lee H, Zhang L, Iniesta AA, Hottes AK, Tan MH, Hillson NJ, Hu P, Shapiro L, McAdams HH.
Nat Biotechnol.
2007;
25
(5):
584-92
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Systems biology of Caulobacter.
Laub MT,
Shapiro L, McAdams HH.
Annu Rev Genet.
2007:
41
429-41
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A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator.
McGrath PT,
Iniesta AA, Ryan KR, Shapiro L, McAdams HH.
Cell.
2006;
124
(3):
535-47
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A phospho-signaling pathway controls the localization and activity of a protease complex critical for bacterial cell cycle progression.
Iniesta AA,
McGrath PT, Reisenauer A, McAdams HH, Shapiro L.
Proc Natl Acad Sci U S A.
2006;
103
(29):
10935-40
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Bacterial stalks are nutrient-scavenging antennas.
McAdams HH,
Proc Natl Acad Sci U S A.
2006;
103
(31):
11435-6
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Cytokinesis signals truncation of the PodJ polarity factor by a cell cycle-regulated protease.
Chen JC,
Hottes AK, McAdams HH, McGrath PT, Viollier PH, Shapiro L.
EMBO J.
2006;
25
(2):
377-86
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Graemlin: general and robust alignment of multiple large interaction networks.
Flannick J,
Novak A, Srinivasan BS, McAdams HH, Batzoglou S.
Genome Res.
2006;
16
(9):
1169-81
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Integrated Protein Interaction Networks for 11 Microbes
Srinivasan, B.,
Novak A, Flannick J, Batzoglou S, McAdams H..
Proceedings of the Tenth Annual International Conference on Computational Molecular Biology, (RECOMB 2006).
2006:
1-14
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Conserved modular design of an oxygen sensory/signaling network with species-specific output.
Crosson S,
McGrath PT, Stephens C, McAdams HH, Shapiro L.
Proc Natl Acad Sci U S A.
2005;
102
(22):
8018-23
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Distinct constrictive processes, separated in time and space, divide caulobacter inner and outer membranes.
Judd EM,
Comolli LR, Chen JC, Downing KH, Moerner WE, McAdams HH.
J Bacteriol.
2005;
187
(20):
6874-82
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DnaA coordinates replication initiation and cell cycle transcription in Caulobacter crescentus.
Hottes AK,
Shapiro L, McAdams HH.
Mol Microbiol.
2005;
58
(5):
1340-53
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Global approaches to the bacterial cell as an integrated system
M. T. Laub,
Lucy Shapiro, Harley McAdams.
in The Bacterial Chrosome, edited by N. Patrick Higgins, ASM Press.
2005
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Integrated Protein Interaction Networks for 230 Microbes
Srinivasan, B.,
A. F. Novak, J. A. Flannick, S. Batzoglou, H. H. McAdams.
BCATS.
2005
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Whole-genome transcriptional analysis of heavy metal stresses in Caulobacter crescentus.
Hu P,
Brodie EL, Suzuki Y, McAdams HH, Andersen GL.
J Bacteriol.
2005;
187
(24):
8437-49
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A genetic oscillator and the regulation of cell cycle progression in Caulobacter crescentus.
Crosson S,
McAdams H, Shapiro L.
Cell Cycle.
2004;
3
(10):
1252-4
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Codon usage between genomes is constrained by genome-wide mutational processes.
Chen SL,
Lee W, Hottes AK, Shapiro L, McAdams HH.
Proc Natl Acad Sci U S A.
2004;
101
(10):
3480-5
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Genomics-Based Analysis of the Bacterial Cell Cycle
Laub, M.T.,
McAdams, H. H., Shapiro L..
Microbial Genomes, Ed. by Fraser, C. M., Read, T., Nelson, K. E..
2004
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Oscillating global regulators control the genetic circuit driving a bacterial cell cycle.
Holtzendorff J,
Hung D, Brende P, Reisenauer A, Viollier PH, McAdams HH, Shapiro L.
Science.
2004;
304
(5673):
983-7
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Rapid and sequential movement of individual chromosomal loci to specific subcellular locations during bacterial DNA replication.
Viollier PH,
Thanbichler M, McGrath PT, West L, Meewan M, McAdams HH, Shapiro L.
Proc Natl Acad Sci U S A.
2004;
101
(25):
9257-62
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Setting the pace: mechanisms tying Caulobacter cell-cycle progression to macroscopic cellular events.
McGrath PT,
Viollier P, McAdams HH.
Curr Opin Microbiol.
2004;
7
(2):
192-7
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The evolution of genetic regulatory systems in bacteria.
McAdams HH,
Srinivasan B, Arkin AP.
Nat Rev Genet.
2004;
5
(3):
169-78
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Transcriptional profiling of Caulobacter crescentus during growth on complex and minimal media.
Hottes AK,
Meewan M, Yang D, Arana N, Romero P, McAdams HH, Stephens C.
J Bacteriol.
2004;
186
(5):
1448-61
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Visualization of the movement of single histidine kinase molecules in live Caulobacter cells.
Deich J,
Judd EM, McAdams HH, Moerner WE.
Proc Natl Acad Sci U S A.
2004;
101
(45):
15921-6
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A bacterial cell-cycle regulatory network operating in time and space.
McAdams HH,
Shapiro L.
Science.
2003;
301
(5641):
1874-7
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Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter.
Judd EM,
Ryan KR, Moerner WE, Shapiro L, McAdams HH.
Proc Natl Acad Sci U S A.
2003;
100
(14):
8235-40
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Generating and exploiting polarity in bacteria.
Shapiro L,
McAdams HH, Losick R.
Science.
2002;
298
(5600):
1942-6
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Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle.
Laub MT,
Chen SL, Shapiro L, McAdams HH.
Proc Natl Acad Sci U S A.
2002;
99
(7):
4632-7
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Global analysis of the genetic network controlling a bacterial cell cycle.
Laub MT,
McAdams HH, Feldblyum T, Fraser CM, Shapiro L.
Science.
2000;
290
(5499):
2144-8
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Toggles and oscillators: new genetic circuit designs.
Judd EM,
Laub MT, McAdams HH.
Bioessays.
2000;
22
(6):
507-9
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Towards a circuit engineering discipline.
McAdams HH,
Arkin A.
Curr Biol.
2000;
10
(8):
R318-20
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It's a noisy business! Genetic regulation at the nanomolar scale.
McAdams HH,
Arkin A.
Trends Genet.
1999;
15
(2):
65-9
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Simulation of prokaryotic genetic circuits.
McAdams HH,
Arkin A.
Annu Rev Biophys Biomol Struct.
1998:
27
199-224
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Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells.
Arkin A,
Ross J, McAdams HH.
Genetics.
1998;
149
(4):
1633-48
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Stochastic mechanisms in gene expression.
McAdams HH,
Arkin A.
Proc Natl Acad Sci U S A.
1997;
94
(3):
814-9
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Circuit simulation of genetic networks.
McAdams HH,
Shapiro L.
Science.
1995;
269
(5224):
650-6
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Dynamic nuclear polarization of liquid helium-three by optical pumping
McAdams, H. H.,
Walters, G. K..
Phys. Rev..
1968;
170
(1):
276
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New Liquid 4HE Experimental cryostat
McAdams, H. H.,
Rev. Sci. Instr..
1968;
39
(1)
-
Dynamic polarization of liquid helium three
McAdams, H. H.,
Walters, G. K..
Physical Review Letters.
1967;
18
(12):
436
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