Yvonne Maldonado

Clinical Focus

• Infectious Diseases, Pediatric
• Pediatric Infectious Disease

Professional Education

Postdoctoral Advisees

  Andrew Anglemyer   Marisa Holubar   Candice McNeil

Graduate & Fellowship Program Affiliations

• Epidemiology
• Infectious Diseases
• Pediatrics

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information

Current Research Interests

The research I have conducted has been focused on epidemiologic aspects of viral vaccine development and prevention of perinatal HIV transmission. A major project has been to identify the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) among children living in developing areas of the world, where OPV immunogenicity is poor. We have identified several factors which affect the poor immunogenicity of OPV and will conduct clinical studies to attempt to improve immunogenicity. We are now working on ways to understand the transmission and circulation of polio vaccine derived viruses, which may cause polio, and how to use this information in global eradication of polio. I also work on perinatal HIV infection, including strategies to prevent breastfeeding transmission in developing settings as well as understanding how to maximize prevention strategies among pregnant women in developed countries.

A second recent project has been to define the ontogeny of the immune response to measles vaccine among young infants. The purpose is to identify specific humoral and cell-mediated immune responses to measles vaccine which affect vaccine immunogenicity and induce the immunosuppressive effects associated with measles vaccination.

A final project I have conducted since 1989 involves a long term natural history study of infants with perinatal HIV exposure and infection. This computer-based study involves following all HIV-exposed and infected infants living in the Northern California and defining factors associated with progression of HIV-related disease.

Publications

• Epidemiologic trends in penile anomalies and hypospadias in the state of California, 1985-2006. Elliott CS, Halpern MS, Paik J, Maldonado Y, Shortliffe LD. J Pediatr Urol. 2011; 7 (3): 294-8
• Hematologic and Immunologic Parameters in Zimbabwean Infants: A Case for Using Local Reference Intervals to Monitor Toxicities in Clinical Trials. Troy SB, Rowhani-Rahbar A, Dyner L, Musingwini G, Shetty AK, Woelk G, Stranix-Chibanda L, Nathoo K, Maldonado YA. J Trop Pediatr. 2011
• Rural HIV-infected women's access to medical care: ongoing needs in California. Sarnquist CC, Soni S, Hwang H, Topol BB, Mutima S, Maldonado YA. AIDS Care. 2011; 23 (7): 792-6
• Use of a novel real-time PCR assay to detect oral polio vaccine shedding and reversion in stool and sewage samples after a mexican national immunization day. Troy SB, Ferreyra-Reyes L, Huang C, Mahmud N, Lee YJ, Canizales-Quintero S, Flaster H, B�ez-Salda�a R, Garc�a-Garc�a L, Maldonado Y. J Clin Microbiol. 2011; 49 (5): 1777-83
• How racial and ethnic groupings may mask disparities: the importance of separating Pacific Islanders from Asians in prenatal care data. Sarnquist CC, Grieb EM, Maldonado YA. Matern Child Health J. 2010; 14 (4): 635-41