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1 - 10 of 18 results for: PATH

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PATH 101: Cancer Biology (CBIO 101)

Experimental approaches to understanding the origins, diagnosis, and treatment of cancer. Focus on key experiments and discoveries with emphasis on genetics, molecular biology, and cell biology. Topics include carcinogens, tumor virology, oncogenes, tumor suppressor genes, cell cycle regulation, angiogenesis, invasion and metastasis, cancer genomics, cancer epidemiology, and cancer therapies. Discussion sections based on primary research articles that describe key experiments in the field. Prerequisite: Biology or Human Biology core or equivalent, or consent of instructor.
Terms: Win | Units: 4 | Grading: Letter or Credit/No Credit
Instructors: Lipsick, J.

PATH 103Q: Lymphocyte Migration

Preference to sophomores. How lymphocytes leave the blood stream and enter tissues to participate in immune surveillance and the development of inflammation. Known as lymphocyte migration, this process involves a complex series of adhesion, activation and diapedesis events. The cellular mechanisms involved in lymphocyte migration, including lymphocyte adhesion molecules that interact with their counter-receptors on endothelial cells, and molecules, including cytokines and chemokines, that attract or activate lymphocytes. The roles of these molecules in the development of human diseases such as asthma, type 1 diabetes, and multiple sclerosis.
Terms: Aut | Units: 1 | Grading: Satisfactory/No Credit
Instructors: Michie, S.

PATH 105Q: Final Analysis: The Autopsy as a Tool of Medical Inquiry

Preference to sophomores. Based on review of patient medical histories and examination of formalin-fixed and unfixed tissues from autopsy. Student-directed problem-solving; students develop learning objectives for each case, and present findings. The effect of disease on normal structure and function, ethics of patient care, allocation of medical resources, efficiency of therapy, and medical error. Prerequisite: hepatitis-B vaccination; free vaccinations during the winter for accepted students. Deadline to apply is noon, November 30, 2009.
Terms: Spr | Units: 3 | Grading: Satisfactory/No Credit
Instructors: Connolly, A.

PATH 199: Undergraduate Research

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum | Units: 1-18 | Repeatable for credit | Grading: Ltr-CR/NC
Instructors: Arber, D.; Atwater, S.; Axelrod, J.; Banaei, N.; B... more instructors for PATH 199 »
Instructors: Arber, D.; Atwater, S.; Axelrod, J.; Banaei, N.; Baron, E.; Berry, G.; Bogyo, M.; Bowen, R.; Butcher, E.; Cherry, A.; Cleary, M.; Connolly, A.; Cornbleet, P.; Cowan, T.; Crabtree, G.; Engleman, E.; Faix, J.; Fire, A.; Fontaine, M.; Foung, S.; Galel, S.; Galli, S.; Geaghan, S.; George, T.; Gonzalez, C.; Goodnough, L.; Graef, I.; Gratzinger, D.; Haddix, T.; Hendrickson, M.; Higgins, J.; Jensen, K.; Kambham, N.; Kempson, R.; Kong, C.; Lipsick, J.; Longacre, T.; Lu, B.; Manning, M.; McKenney, J.; Michie, S.; Natkunam, Y.; Pai, R.; Patterson, B.; Pollack, J.; Regula, D.; Rouse, R.; Schrijver, I.; Schwartz, E.; Sidow, A.; Sobel, R.; Sundram, U.; Sussman, H.; Tan, B.; Tyan, D.; Viele, M.; Vogel, H.; Wang, T.; Warnke, R.; Weissman, I.; Wernig, M.; West, R.; Zehnder, J.; van de Rijn, J.

PATH 206: Epigenetics (BIO 156, BIO 256, GENE 206)

For graduate students in the Biosciences and upper level Biology undergraduates. Mechanisms by which phenotypes not determined by the DNA sequence are stably inherited in successive cell divisions. From the discovery of position-effect variegation in Drosophila in the 1920s to present-day studies of covalent modifications of histones and DNA methylation. Topics include: position effect, gene silencing, heterochromatin, centromere identity, genomic imprinting, histone code, variant histones, and the role of epigenetics in cancer. Prerequisite: BIO41 and BIO42 , or GENE 203, or consent of instructor.
Terms: Spr, alternate years, not given next year | Units: 2 | Grading: Letter or Credit/No Credit
Instructors: Gozani, O.; Lipsick, J.

PATH 210: Stem Cells in Development and Disease

Molecular and cellular mechanisms underlying the basic self-renewal and differentiation properties of stem cells in multiple tissues and organisms. How abnormal stem cell behavior may contribute to diseases such as cancer. How to manipulate stem cell behavior in vitro or in vivo for therapeutic purposes. Classical papers and recent literatures in the field of stem cell biology. Open to graduate, medical, and advanced undergraduate students. Prerequisite: consent of instructor.
Terms: Aut | Units: 1-2 | Grading: Med Opt
Instructors: Lu, B.

PATH 213: Gross Autopsy Pathology Laboratory

Examine/discuss unfixed dissected organs from current autopsies and correlate morphologic findings with the clinical history. Students view postmortem examinations and may participate (in a small group) in one postmortem examination with the assistance of residents and staff, and present the case to the class. Class scheduling is flexible. Additional unit for participation in a postmortem examination. Pre- or corequisite: HHD.
Terms: Aut, Win | Units: 2-3 | Grading: Medical School MD Grades
Instructors: Regula, D.

PATH 218: Computational Analysis of Biological Images (GENE 218)

Physical and computational tools for acquisition, processing, interpretation, and archiving of biological images. Emphasis is on digital microscopy.
Terms: alternate years, given next year | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

PATH 233: The Biology of Small Modulatory RNAs (GENE 233, MI 233)

Open to graduate and medical students. How recent discoveries of miRNA, RNA interference, and short interfering RNAs reveal potentially widespread gene regulatory mechanisms mediated by small modulatory RNAs during animal and plant development. Required paper proposing novel research.
Terms: alternate years, given next year | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)

PATH 234: Fundamentals of RNA Biology (GENE 234, MI 234)

For graduate or medical students and (if space allows) to active participants from other segments of the Stanford Community (e.g., TGR students); undergraduates by instructor consent. Fundamental issues of RNA biology, with the goal of setting a foundation for students to explore the expanding world of RNA-based regulation. Each week a topic is covered by a faculty lecture and journal club presentations by students.
Terms: Aut | Units: 2 | Grading: Medical Option (Med-Ltr-CR/NC)
Instructors: Chen, C.; Fire, A.; Sarnow, P.
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