1 - 10 of 15 results for: DBIO

The biological, medical, and social aspects of normal and abnormal human development. Topics: in vitro fertilization and embryo transfer; gene and cell therapy; gametogenesis; pattern formation in the nervous system and limb development; gene and grand multiple pregnancies; prematurity, in utero effects of teratogens; sex determination and differentiation; growth control; gigantism and dwarfism; neural tube defects; cardiac morphogenesis; progress in the developmental biology of humans. Limited enrollment. Prerequisites: Human Biology or Biology core, or consent of instructor.

Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.

Mechanisms that direct human development from conception to birth. Conserved molecular and cellular pathways regulate tissue and organ development; errors in these pathways result in congenital anomalies and human diseases. Topics: molecules regulating development, cell induction, developmental gene regulation, cell migration, programmed cell death, pattern formation, stem cells, cell lineage, and development of major organ systems. Emphasis on links between development and clinically significant topics including infertility, assisted reproductive technologies, contraception, prenatal diagnosis, multiparity, teratogenesis, inherited birth defects, fetal therapy, adolescence, cancer, and aging.

Primary and current literature in basic and clinical science aspects of assisted reproductive technologies (ART), and demonstrations of current ART techniques including in vitro fertilization and embryo culture, and micromanipulation procedures such as intracytoplasmic sperm injection and embryo biopsy and cryopreservation.Class only may be taken for 1 unit. 2 units includes papers and attendance at clinical demonstrations. 3 units includes a term paper. Recommended: DBIO 201, or consent of instructors.

For graduate students in Bioscience programs; may be appropriate for graduate students in other programs. The genetic toolbox. Examples of analytic methods, genetic manipulation, genome analysis, and human genetics. Emphasis is on use of genetic tools in dissecting complex biological pathways, developmental processes, and regulatory systems. Faculty-led discussion sections with evaluation of papers. Students with minimal experience in genetics should prepare by working out problems in college level textbooks.

Current areas of research in developmental biology. How organismic complexity is generated during embryonic and post-embryonic development. The roles of genetic networks, induction events, cell lineage, maternal inheritance, cell-cell communication, and hormonal control in developmental processes in well-studied organisms such as vertebrates, insects, and nematodes. Team-taught. Students meet with faculty to discuss current papers from the literature. Prerequisite: graduate standing, consent of instructor. Recommended: familiarity with basic techniques and experimental rationales of molecular biology, biochemistry, and genetics.

Literature discussion in conjunction with the Frontiers in Biological Research seminar series in which investigators present current work. Students and faculty meet beforehand to discuss papers from the speaker¿s primary research literature. Students meet with the speaker after the seminar to discuss their research and future direction, commonly used techniques to study problems in biology, and comparison between the genetic and biochemical approaches in biological research.

Current research literature on genetic mechanisms of aging in animals and human beings. Topics include: mitochondria mutations, insulin-like signaling, sirtuins, aging in flies and worms, stem cells, human progeria, and centenarian studies. Prerequisite: GENE 203.

The role of stem cells in human development and potential for treating disease. Guest lectures by biologists, ethicists, and legal scholars. Prerequisites: 2A,B, or consent of instructor.