{"result":[{"lastName":"Kwiatkowski","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=8725&type=small&showNoImage","displayName":"Adam Kwiatkowski","firstName":"Adam","href":"https://med.stanford.edu/profiles/Adam_Kwiatkowski","researchInterest":""},{"lastName":"Rasmussen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=9637&type=small&showNoImage","displayName":"Soren Rasmussen","firstName":"Soren","href":"https://med.stanford.edu/profiles/Soren_Rasmussen","researchInterest":""},{"lastName":"Pande","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemistry"},{"appointment":"Associate Professor (By courtesy),Structural Biology"},{"appointment":"Associate Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Chemistry","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=6184&type=small&showNoImage","displayName":"Vijay Pande","firstName":"Vijay","href":"https://med.stanford.edu/profiles/Vijay_Pande","researchInterest":"The central theme of our research is to develop and apply novel theoretical methods to understand the physical properties of biological molecules, such as proteins, nucleic acids, lipid membranes, and small molecule therapeutics (eg protein folding or lipid vesicle fusion).   As these phenomena are complex, my research employs novel theoretical and computational techniques.  We apply these methods to develop novel therapeutics for protein misfolding diseases, such as Alzheimer's Disease."},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"https://med.stanford.edu/profiles/Michael_Levitt","researchInterest":"having pioneered, we (a) predict folding of a polypeptide and RNA chains into a unique native-structure, we (b) model protein structure using the well-established paradigms that similar protein sequences imply similar three-dimensional structures, and (c) we are focusing on mesoscale modeling of large macromolecular complexes such as RNA polymerase and the mammalian chaperonin."},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"https://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Nygaard","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=17605&type=small&showNoImage","displayName":"Rie Nygaard","firstName":"Rie","href":"https://med.stanford.edu/profiles/Rie_Nygaard","researchInterest":""},{"lastName":"Harbury","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Biochemistry","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4433&type=small&showNoImage","displayName":"Pehr Harbury","firstName":"Pehr","href":"https://med.stanford.edu/profiles/Pehr_Harbury","researchInterest":"Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides."},{"lastName":"Kaiser","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=10008&type=small&showNoImage","displayName":"Stephen Kaiser","firstName":"Stephen","href":"https://med.stanford.edu/profiles/Stephen_Kaiser","researchInterest":""},{"lastName":"Kobilka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4300&type=small&showNoImage","displayName":"Brian Kobilka","firstName":"Brian","href":"https://med.stanford.edu/profiles/Brian_Kobilka","researchInterest":"Structure, function and physiology of adrenergic receptors."},{"lastName":"Fung","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=13345&type=small&showNoImage","displayName":"Juan Jose Fung","firstName":"Juan Jose","href":"https://med.stanford.edu/profiles/Juan Jose_Fung","researchInterest":""},{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","displayName":"Chris Garcia","firstName":"Chris","href":"https://med.stanford.edu/profiles/Chris_Garcia","researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches."},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=10975&type=small&showNoImage","displayName":"Song Liu","firstName":"Song","href":"https://med.stanford.edu/profiles/Song_Liu","researchInterest":""},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"https://med.stanford.edu/profiles/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during repair and regeneration after tissue injury."},{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"https://med.stanford.edu/profiles/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Baldwin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=6816&type=small&showNoImage","displayName":"Robert Baldwin","firstName":"Robert","href":"https://med.stanford.edu/profiles/Robert_Baldwin","researchInterest":"I closed my laboratory when I retired in 1998.  I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation,  and to write reviews."},{"lastName":"Vivona","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=12671&type=small&showNoImage","displayName":"Sandro Vivona","firstName":"Sandro","href":"https://med.stanford.edu/profiles/Sandro_Vivona","researchInterest":""},{"lastName":"Brutlag","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biochemistry"},{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor Emeritus,Biochemistry","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4624&type=small&showNoImage","displayName":"Douglas L. Brutlag","firstName":"Douglas","href":"https://med.stanford.edu/profiles/Douglas_Brutlag","researchInterest":"My primary interest is to understand the flow of information from the genome to the phenotype of an organism.  This interest includes predicting the structure and function of genes and proteins  from their primary sequence, predicting function from structure and finally simulating protein folding and ligand docking.  These goals are the same as the goals of molecular biology, however, we use primarily computational approaches."},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","displayName":"Oleg Jardetzky","firstName":"Oleg","href":"https://med.stanford.edu/profiles/Oleg_Jardetzky","researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure"},{"lastName":"Borghi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=9555&type=small&showNoImage","displayName":"Nicolas Borghi","firstName":"Nicolas","href":"https://med.stanford.edu/profiles/Nicolas_Borghi","researchInterest":""},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"https://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Boxer","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=8050&type=small&showNoImage","displayName":"Steven Boxer","firstName":"Steven","href":"https://med.stanford.edu/profiles/Steven_Boxer","researchInterest":""},{"lastName":"van Amerongen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=9613&type=small&showNoImage","displayName":"Renee van Amerongen","firstName":"Renee","href":"https://med.stanford.edu/profiles/Renee_van Amerongen","researchInterest":"Alternative modes of Wnt-signal transduction"},{"lastName":"Chu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=15846&type=small&showNoImage","displayName":"Matthew Chu","firstName":"Ling Hon","href":"https://med.stanford.edu/profiles/Ling Hon_Chu","researchInterest":""},{"lastName":"Kuo","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Medical fellow, Pediatrics","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=10642&type=small&showNoImage","displayName":"Christin S Kuo","firstName":"Christin","href":"https://med.stanford.edu/profiles/Christin_Kuo","researchInterest":""},{"lastName":"Yizhar","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"https://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","displayName":"Ofer Yizhar","firstName":"Ofer","href":"https://med.stanford.edu/profiles/Ofer_Yizhar","researchInterest":""}]}